Definition: The term 'Chikungunya Vaccine, Live' refers to a live attenuated vaccine that specifically targets Chikungunya virus to protect against the disease. It is an approved and commonly used vaccine for prevention and control of the mosquito-borne disease. Chikungunya is a tropical virus transmitted by the Anopheles mosquito. The disease typically begins with a fever, followed by rash, joint pain, and neurological symptoms. Symptoms are usually severe, but they can be mild or even asymptomatic in some individuals. Chikungunya usually lasts for several weeks to months. Chikungunya is spread through direct contact with the saliva of an infected person. Mosquitoes that carry the virus feed on the body fluids of humans, which can then become contaminated. These mosquitoes are commonly found around water sources like swimming pools, fountains, and standing water areas. A live attenuated vaccine, such as Chikungunya Vaccine, Live, is a type of vaccine developed to prevent the spread of the Chikungunya virus from person to person through vaccination. The vaccine contains weakened or killed versions of the Chikungunya virus that are produced in an animal model. This way, individuals who receive this vaccine do not get sick with the actual virus. The live attenuated vaccine protects against specific strains and types of Chikungunya virus present in the environment rather than the live virus itself. This makes it more effective at preventing transmission from person to person compared to a live virus that can cause disease in infected individuals. The vaccine is typically administered through injection or inhalation, depending on the type of vaccine. The most common form of administration involves the injection of the live attenuated vaccine into the arm, while some vaccines are taken orally. In summary, the Chikungunya Vaccine, Live is a live attenuated vaccine that specifically targets Chikungunya virus to protect against the disease by targeting the virus's DNA and RNA. It is an approved and commonly used vaccination for prevention and control of the mosquito-borne disease.
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